micro rna การใช้

• Micro RNAs are important regulators of almost all cellular processes such as survival, differentiation.
• These micro RNAs have pivotal roles in development and physiology of muscle tissues including the heart.
• Other potential future biomarkers include micro RNA molecules, which cancerous cells express more of than healthy ones.
• The distance between the PAZ and RNaseIII domains is determined by the angle of the connector helix and influences the length of the micro RNA product.
• In NSUN2 deficient cells, the loss of cytosine-5 methylation causes incorrect processing into small RNA fragments that end up functioning similar to micro RNAs.
• Micro RNAs ( miRNA ) are single-stranded transcribed RNAs of 19 25 nucleotides in length that are generated from endogenous hairpin structured transcripts throughout the genome.
• In addition to the BDNF gene, micro RNAs ( miRNAs ) play a role in mood disorders, and transcript levels are suggested in SSRI treatment efficacy.
• Some imprinted genes code for regulatory RNA elements such as lncRNA, small nucleolar RNA, and micro RNA, so the expression of these genes results in the silencing of some other gene.
• The expression of " FOXP2 " is subject to post-transcriptional regulation, particularly micro RNA, which binds to multiple miRNA binding-sites in the neocortex, causing the repression of FOXP2 3 UTR.
• The "'miR-1 microRNA precursor "'is a small micro RNA that regulates its target protein's expression in the cell . microRNAs are transcribed as ~ 70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~ 22 nucleotide products.